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Leto Kyritsi

Biologist - Bioinformatician

Leto Kyritsi studied Molecular Biology and Genetics, and obtained an MSc in Biosystems and Informatics from the University of Liverpool.

In Liverpool she did protein expression research for the University's Department of Medicine (Oncology Research Unit & TheRyte anti-cancer drug discovery company) where she initiated a project for modelling protein-protein interaction networks in normal vs. cancer cells as scale-free networks. She was a member of the Biocomputation and Computational Biology Group, led by Ray Paton, with whom she collaborated for the "Multidisciplinary Approaches to Theory in Medicine" book series (Elsevier Science).

She is a doctoral student at the Aristotle University of Thessaloniki, Department of Chemistry, under the supervision of Profs. Theodora Choli-Papadopoulou, Stergios Logothetidis and Aristea Pantazaki. Her research entails investigating the biochemistry of ultradilute solutions and the effect of ultradilute solutions on cells and tissues of various types.

Publications

  • Hilmar Warenius, Leto Kyritsi, Ian Grierson, Amanda Howarth, Laurence Seabra, Mark Jones, Carole Thomas, Paul Browning, Rosalind White Spontaneous regression of human cancer cells in vitro: potential role of disruption of Cdk1/Cdk4 co-expression. Anticancer research, 2009 29(6):1933-41.
  • Warenius H., Seabra L., Kyritsi L., White R., Dormer R., Anandappa S., Thomas C., Howarth A. Theranostic proteomic profiling of cyclins, cyclin dependent kinases and ras in human cancer cell lines is dependent on p53 mutational status. Int J Oncol. 2008 Apr; 32(4):895-907.
  • Warenius H., Howarth A., Seabra L., Kyritsi L., Dormer R., Anandappa S., Thomas C. Dynamic heterogeneity of proteomic expression in human cancer cells does not affect Cdk1-Cdk4 co-expression. J Exp Ther Oncol. 2008; 7(3):237-54.
  • Warenius H., Kyritsi L., Grierson I., Howarth A., Seabra L., Jones M., Thomas C., Browning P., White R. Spontaneous regression of human cancer cells in-vitro, Anticancer Res. 2009 Jun; 29(6):1933-41.
  • MSc thesis: "Analysis, design and implementation of a program to explore ecologies of biological information on the World Wide Web". The project entailed the construction of a tool for extensive interaction with the Web and automated textual data mining and analysis, and was implemented in Python.

Presentations

  • Warenius H., Seabra L., Kyritsi L., Jones M., Thomas C., White R., Browning P., Howarth A. Proteomic co-expression patterns of Critical Normal Genes are found in human cancer cell lines but not in normal cells. British Cancer Research Conference. Manchester 2004.
  • Warenius H., Kyritsi L. Neostasis as a therapeutically vulnerable homogeneous component of robust cancer systems. 6th International Conference on Pathways, Networks, and Systems Medicine. Crete 2008.
  • Kyritsi L., Choli-Papadopoulou Th. "Biphasic response effects on cells from ultra-low doses of chemotoxic agents" 66th Conference of the Hellenic Society for Molecular Biology & Biochemistry. Athens 2016.

Talks

    • "Biphasic response effects on cells from ultra-low doses of chemotoxic agents", talk given at the 17th Hellenic Congress on Homeopathic Medicine, Athens 2015.
    • "Networks in Biology" talk given in the context of the conference "Networks in Art & Life", AKTO School of Art, Athens 2015.
    • "The Biochemistry of the Homeopathic Idiosyncrasy" : talk given with Spiros Kivellos, MD at the 16th Hellenic Congress on Homeopathic Medicine, Ermoupolis, Syros, 2012.

    Contact Information: l.kyritsi (at) yahoo.com

     

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